Nikolai Köhler M.Sc.

Research Associate, Chair of Experimental Bioinformatics | Technical University of Munich

Nikolai Köhler is a member of the bidt Junior Research Group LipiTUM at the Technical University of Munich, holding a Master’s Degree in Molecular Biotechnology from TUM. In his doctorate, he focuses on computational methods for analysing metabolite data and metabolic networks in a systems biology context.

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Participations and Contributions
Publications
Participations and Contributions
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Digital society

Enabling precision medicine with AI

Blog
25 May 2021

AI and related technologies keep shaping our society, providing us with more and more solutions that seemed impossible only a few years ago. This blog post gives an insight into the research field of bioinformatics, showing…

Publications

  • Häcker, Deborah; Siebert, Kolja; Smith, Byron J.; Köhler, Nikolai; Riva, Alessandra; Mahapatra, Aritra; Heimes, Helena; Nie, Jiatong; Metwaly, Amira; Hölz, Hannes; Manz, Quirin; De Zen, Federica; Heetmeyer, Jeannine; Socas, Katharina; Le Thi, Giang; Meng, Chen; Kleigrewe, Karin; Pauling, Josch K.; Neuhaus, Klaus; List, Markus; Pollard, Katherine S.; Schwerd, Tobias; Haller, Dirk (2024)

    Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease

    Journal article
    https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(24)00359-7
    Project: NWG-LipiTUM
  • Köhler, Nikolai; Höring, Marcus; Czepukojc, Beate; Rose, Tim Daniel; Buechler, Christa; Kröhler, Tarek; Haybaeck, Johannes; Liebisch, Gerhard; Pauling, Josch K.; Kessler, Sonja M.; Kiemer, Alexandra K. (2022)

    Kupffer cells are protective in alcoholic steatosis

    Journal article
    Biochimica et biophysica acta. Molecular basis of disease, Volume: 1868, Nr. 6, P. 166398
    DOI: 10.1016/j.bbadis.2022.166398
    Project: NWG-LipiTUM
  • Rose, Tim D.; Köhler, Nikolai; Falk, Lisa; Klischat, Lucie; Lazareva, Olga E.; Pauling, Josch K. (2023)

    Lipid network and moiety analysis for revealing enzymatic dysregulation and mechanistic alterations from lipidomics data

    Journal article
    Briefings in bioinformatics, Volume: 24, Nr. 1
    DOI: 10.1093/bib/bbac572
    Project: NWG
  • Rose, Tim D.; Köhler, Nikolai; Falk, Lisa; Klischat, Lucie; Lazareva, Olga E.; Pauling, Josch K. (2022)

    Lipid network and moiety analysis for revealing enzymatic dysregulation and mechanistic alterations from lipidomics data

    Book
    DOI: 10.1101/2022.02.04.479101
    Project: NWG-LipiTUM
  • Würf, Vivian; Köhler, Nikolai; Molnar, Florian; Hahnefeld, Lisa; Gurke, Robert; Witting, Michael; Pauling, Josch K. (2024)

    LipiDetective a deep learning model for the identification of molecular lipid species in tandem mass spectra

    Internet document
    https://www.biorxiv.org/content/10.1101/2024.10.07.617094v3
    Project: NWG-LipiTUM
  • Rose, Tim Daniel; Bechtler, Thibault; Ciora, Octavia-Andreea; Anh Lilian Le, Kim; Molnar, Florian; Köhler, Nikolai; Baumbach, Jan; Röttger, Richard; Pauling, Josch Konstantin (2022)

    MoSBi: Automated signature mining for molecular stratification and subtyping

    Conference paper
    Proceedings of the National Academy of Sciences of the United States of America, Volume: 119, Nr. 16, P. 2118210119
    DOI: 10.1073/pnas.2118210119
    Project: NWG-LipiTUM
  • Damiani, Tito; Bonciarelli, Stefano; Thallinger, Gerhard G.; Koehler, Nikolai; Krettler, Christoph A.; Salihoğlu, Arif K.; Korf, Ansgar; Pauling, Josch K.; Pluskal, Tomáš; Ni, Zhixu; Goracci, Laura (2023)

    Software and Computational Tools for LC-MS-Based Epilipidomics: Challenges and Solutions

    Journal article
    Analytical chemistry, Volume: 95, Nr. 1, P. 287-303
    DOI: 10.1021/acs.analchem.2c04406
    Project: NWG-LipiTUM
  • Dieckmann, Sebastian; Strohmeyer, Akim; Willershäuser, Monja; Maurer, Stefanie F.; Wurst, Wolfgang; Marschall, Susan; Angelis, Martin Hrabe de; Kühn, Ralf; Worthmann, Anna; Fuh, Marceline M.; Heeren, Joerg; Köhler, Nikolai; Pauling, Josch K.; Klingenspor, Martin (2022)

    Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1

    Journal article
    American journal of physiology. Endocrinology and metabolism, Volume: 322, Nr. 2, P. 85
    DOI: 10.1152/ajpendo.00278.2021
    Project: NWG-LipiTUM
  • Würf, Vivian; Köhler, Nikolai; Molnar, Florian; Hahnefeld, Lisa; Gurke, Robert; Witting, Michael; Pauling, Josch K. (2024)

    LipiDetective a deep learning model for the identification of molecular lipid species in tandem mass spectra

    Internet document
    https://www.biorxiv.org/content/10.1101/2024.10.07.617094v3
    Project: NWG-LipiTUM
  • Häcker, Deborah; Siebert, Kolja; Smith, Byron J.; Köhler, Nikolai; Riva, Alessandra; Mahapatra, Aritra; Heimes, Helena; Nie, Jiatong; Metwaly, Amira; Hölz, Hannes; Manz, Quirin; De Zen, Federica; Heetmeyer, Jeannine; Socas, Katharina; Le Thi, Giang; Meng, Chen; Kleigrewe, Karin; Pauling, Josch K.; Neuhaus, Klaus; List, Markus; Pollard, Katherine S.; Schwerd, Tobias; Haller, Dirk (2024)

    Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease

    Journal article
    https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(24)00359-7
    Project: NWG-LipiTUM
  • Rose, Tim D.; Köhler, Nikolai; Falk, Lisa; Klischat, Lucie; Lazareva, Olga E.; Pauling, Josch K. (2023)

    Lipid network and moiety analysis for revealing enzymatic dysregulation and mechanistic alterations from lipidomics data

    Journal article
    Briefings in bioinformatics, Volume: 24, Nr. 1
    DOI: 10.1093/bib/bbac572
    Project: NWG
  • Damiani, Tito; Bonciarelli, Stefano; Thallinger, Gerhard G.; Koehler, Nikolai; Krettler, Christoph A.; Salihoğlu, Arif K.; Korf, Ansgar; Pauling, Josch K.; Pluskal, Tomáš; Ni, Zhixu; Goracci, Laura (2023)

    Software and Computational Tools for LC-MS-Based Epilipidomics: Challenges and Solutions

    Journal article
    Analytical chemistry, Volume: 95, Nr. 1, P. 287-303
    DOI: 10.1021/acs.analchem.2c04406
    Project: NWG-LipiTUM
  • Rose, Tim Daniel; Bechtler, Thibault; Ciora, Octavia-Andreea; Anh Lilian Le, Kim; Molnar, Florian; Köhler, Nikolai; Baumbach, Jan; Röttger, Richard; Pauling, Josch Konstantin (2022)

    MoSBi: Automated signature mining for molecular stratification and subtyping

    Conference paper
    Proceedings of the National Academy of Sciences of the United States of America, Volume: 119, Nr. 16, P. 2118210119
    DOI: 10.1073/pnas.2118210119
    Project: NWG-LipiTUM
  • Rose, Tim D.; Köhler, Nikolai; Falk, Lisa; Klischat, Lucie; Lazareva, Olga E.; Pauling, Josch K. (2022)

    Lipid network and moiety analysis for revealing enzymatic dysregulation and mechanistic alterations from lipidomics data

    Book
    DOI: 10.1101/2022.02.04.479101
    Project: NWG-LipiTUM
  • Köhler, Nikolai; Höring, Marcus; Czepukojc, Beate; Rose, Tim Daniel; Buechler, Christa; Kröhler, Tarek; Haybaeck, Johannes; Liebisch, Gerhard; Pauling, Josch K.; Kessler, Sonja M.; Kiemer, Alexandra K. (2022)

    Kupffer cells are protective in alcoholic steatosis

    Journal article
    Biochimica et biophysica acta. Molecular basis of disease, Volume: 1868, Nr. 6, P. 166398
    DOI: 10.1016/j.bbadis.2022.166398
    Project: NWG-LipiTUM
  • Dieckmann, Sebastian; Strohmeyer, Akim; Willershäuser, Monja; Maurer, Stefanie F.; Wurst, Wolfgang; Marschall, Susan; Angelis, Martin Hrabe de; Kühn, Ralf; Worthmann, Anna; Fuh, Marceline M.; Heeren, Joerg; Köhler, Nikolai; Pauling, Josch K.; Klingenspor, Martin (2022)

    Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1

    Journal article
    American journal of physiology. Endocrinology and metabolism, Volume: 322, Nr. 2, P. 85
    DOI: 10.1152/ajpendo.00278.2021
    Project: NWG-LipiTUM